View Eplerenone Spironolactone Equivalent Dose Background. Spironolactone treats fluid retention in patients with congestive heart failure, cirrhosis, or kidney problems. Your dose may change depending on the level of potassium in your blood.
Spironolactone is used to treat high blood pressure and heart failure. Initial doses should be low (spironolactone 12.5 mg/day eplerenone 25 mg/day), especially in the elderly and those with diabetes or creatinine clearance <50 ml/min. Learn about side effects, interactions and indications.
Spironolactone and eplerenone are the only two mr antagonists on the market at present with spironolactone being more potent on mr but in heart failure, the randomized aldactone evaluation study (rales) reported in 1999 demonstrated that a low dose of spironolactone, when added to.
Do not use a household spoon because. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Switching spironolactone to 150 mg of eplerenone daily resulted in resolution of gynaecomastia and also maintained bp control. The eplerenone dose should be titrated to the target.